Stomatocyte-discocyte-echinocyte sequence of the human red blood cell: evidence for the bilayer- couple hypothesis from membrane mechanics.

نویسندگان

  • Gerald Lim H W
  • Michael Wortis
  • Ranjan Mukhopadhyay
چکیده

Red-cell shape is encoded in the mechanical properties of the membrane. The plasma membrane contributes bending rigidity; the protein-based membrane skeleton contributes stretch and shear elasticity. When both effects are included, membrane mechanics can reproduce in detail the full stomatocyte-discocyte-echinocyte sequence by variation of a single parameter related to the bilayer couple originally introduced by Sheetz and Singer [Sheetz, M. P. & Singer, S. J. (1974) Proc. Natl. Acad. Sci. USA 71, 4457-4461].

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عنوان ژورنال:
  • Proceedings of the National Academy of Sciences of the United States of America

دوره 99 26  شماره 

صفحات  -

تاریخ انتشار 2002